Sjögren sendromu ve primer biliyer siroz birlikteligi
‘’Sjogren’s syndrome and primary biliary cirrhosis’’
Özet
Sjögren sendromu (SS) primer semptomlari kuru göz ve kuru agiz olan kronik otoimmün bir hastaliktir. Primer biliyer siroz (PBS) SS ile birlikte sik görülen bir klinik durumdur. SS’da insidansi %3 ile %9 arasi degisen oranlarda rapor edilmektedir. Her iki hastalikta da otoimmünite duktal epitel hücrelerine dogrudur. SS’lu hastalarda eger serum alkalen fosfataz yüksekligi saptanirsa karaciger biyopsisi ve AMA bakilmasi ile PBS arastirilmalidir. Bu yazida 63 yasinda PBS ve SS olan kadin bir olgu sunumu yapildi.
Abstract
Sjögren’s syndrome (SS), a chronic autoimmune disorder, primarily manifests as dry eyes and mouth. Primary biliary cirrhosis (PBC) is one of the most frequent hepatic diseases associated with SS, with its reported incidence ranging from 3% to 9%. It both diseases, autoimmunity seems to be directed toward the ductal epithelial cells. When SS patients have an elevated alkaline phosphatase level, it is necessary to examine AMA and to perform liver biopsy. A 63-year-old woman with PBC and SS is reported.
