Nisan 2018
Çölyak hastaliginda Helicobacter pylori prevalansinin degerlendirilmesi
Evaluation of Helicobacter pylori prevalence in celiac disease
- Ana Sayfa
- Sayılar
- Nisan 2018
- Çölyak hastaliginda Helicobacter pylori prevalansinin degerlendirilmesi...
2Hacettepe Üniversitesi Saglik Bilimleri Fakültesi Beslenme ve Diyetetik Anabilim Dali, Ankara
Özet
Giris ve Amaç: Helicobacter pylori’nin çölyak hastaligina karsi koru-yucu rolü olabilecegini gösteren çalismalarin yani sira; çölyak hastali-ginda Helicobacter pylori prevalansinin arttigini gösteren çalismalar da mevcuttur. Biz çalismamizda; klinigimizde çölyak hastaligi tanisi almis hastalarda tani aninda Helicobacter pylori prevalansini saptamayi ve yas uyumlu kontrol grubu ile karsilastirmayi amaçladik. Gereç ve Yöntem:Çalismaya 41 çölyak hastasi, yas ve cinsiyet uyumlu dispeptik sikayetleri nedeni ile üst gastrointestinal sistem endoskopisi yapilmis 82 kontrol hastasi dahil edildi. Bulgular: Helicobacter pylori 41 çölyak hastasinin 20’sinde (48,8%), 82 kontrol hastasinin 70’inde (85.4%) tespit edildi. Helicobacter pylori prevalansi çölyak hastalarinda genel popülasyondan daha az saptandi. Sonuç: Çölyak hastaliginin patogenezinde Helicoba-cter pylori’nin rolünü degerlendirmek için çok sayida hasta içeren çok merkezli çalismalara ihtiyaç vardir.
Abstract
Background and Aims: Although studies have reported a protective role of Helicobacter pylori against celiac disease, some studies have shown an increased prevalence of Helicobacter pylori in celiac disease. We aimed to detect the prevalence of Helicobacter pylori at the time of the diagnosis of celiac disease and compared it with an age-matched control group in our clinic. Materials and Methods: In this study, 41 celiac and 82 control patients, with similar age and sex, who underwent an upper gastrointestinal endoscopy for dyspeptic symptoms were in-cluded. Results: Helicobacter pylori was detected in 20 (48.8%) of the 41 celiac patients and in 70 (85.4%) of the 82 control subjects. The prevalence of Helicobacter pylori was lower in celiac patients than in the general population. Conclusion: Multicenter studies including a larger number of patients are needed to assess the role of Helicobacter pylori in the pathogenesis of celiac disease
