Agustos 2011
Tüberküloz ve Crohn hastaligi ayiriminda histopatolojik inceleme yeterli midir?
Is histopathological examination sufficient in the diagnosis of Crohn’s disease in the case of suspected tuberculosis?
- Ana Sayfa
- Sayılar
- Agustos 2011
- Tüberküloz ve Crohn hastaligi ayiriminda histopatolojik inceleme yeterli midir? ...
Özet
Tüberküloz ve Crohn hastaligi, gastrointestinal sistemin benzer bölümlerini etkileyen kronik hastaliklar olup, klinik olarak ayirdedilemezler. Biyopsi materyalinin histopatolojik incelemesi Crohn için, hala altin standart olmasina ragmen, tüberküloz için her zaman yeterli olmayabilir. Bu çalismada, Crohn hastaligi tanisiyla 4 aydir izlenen ve tekrarlanan kolonoskopide alinan örnegin mikroskobik incelemesinde aside rezistan basil görülmesi, kültür ve polimeraz zincir reaksiyonu pozitisigi ile tani konulabilen 19 yasindaki intestinal tüberkülozlu olgu sunulmustur. Ates, karin agrisi, kronik diyare ile basvuran hastalarda barsak biyopsi sonucu Crohn ile uyumlu gelse bile; ayni bölgeyi tutmasi ve benzer klinikle seyretmesi nedeniyle intestinal tüberküloz akilda tutulmali ve taniya yönelik mikrobiyolojik tetkikler mutlaka yapilmalidir.
Abstract
Tuberculosis and Crohn’s disease are chronic diseases affecting similar parts of the gastrointestinal system, and they cannot be differentiated clinically. Histopathological examination of a biopsy remains a gold standard for Crohn’s disease, but this procedure may not be sufficient for diagnosis of intestinal tuberculosis. In this study, a 19-year-old patient with intestinal tuberculosis is presented; the diagnosis was made by direct microscopic examination, culture and polymerase chain reaction positivity for tuberculosis in a secondary colonoscopic examination. In all patients admitted with fever, chronic diarrhea and abdominal pain, intestinal tuberculosis should be kept in mind, and microbiological tests should be performed due to the similar clinical findings and same affected parts of the gastrointestinal system, even if histopathological results are compatible with Crohn’s disease.
