Nisan 2010
Özofagusun 24 saatlik pH-metre izlemine hastanin vücut kitle indeksinin etkisi var mi?
Does body mass index have any impact on 24-hour esophageal pH monitoring results?
- Ana Sayfa
- Sayılar
- Nisan 2010
- Özofagusun 24 saatlik pH-metre izlemine hastanin vücut kitle indeksinin etkisi var mi?...
Özet
Giris ve Amaç: Gastroözefageal reflü hastaligi ve obezite önemli saglik problemlerindendir. Obezite ve gastroözofageal reflü hastaligi arasindaki iliski konusunda yapilan çalisma sonuçlari çeliskilidir. Özofagusun 24 saatlik pH-izlemi gastroözofageal reflü hastaligi tanisinda kullanilan yüksek spesifiteye sahip en objektif tani yöntemidir. Bu çalismamizi, gastroözofageal reflü hastaligi nedeniyle pH-metre yapilan hastalarimizda vücut kitle indeksi ile pH-metre verileri arasinda bir iliski olup olmadigini arastirmak için retrospektif olarak planladik. Gereç ve Yöntem: Özofagusun 24 saatlik pH-metre izleminin yapildigi 207 hasta degerlendirildi. Hastalarin demografik verileri ve pH-metre kayitlari incelendi. Vücut kitle indeksi ile 24 saatlik özofageal pH ölçüm parametreleri arasinda korelasyon analizi yapildi. Ardindan hastalar Dünya Saglik Örgütü'nün vücut kitle indeksi kategorilerine göre gruplara ayrildi ve pH-izlem parametreleri açisindan gruplar arasinda fark olup olmadigi arastirildi. Bulgular: Hastalarin 93 tanesi erkek (%45), 114 tanesi kadindi (%55) ve yas ortalamalari 42 ± 12 yildi (18-74 yas arasinda). Vücut kitle indeksi <25 olan hasta grubu ile ≥25 olan hasta grubu karsilastirildiginda özofageal pH ölçüm parametrelerinden reflü sayisi, uzun reflü sayisi, pH<4 zaman yüzdesi ve total DeMeester skoru vücut kitle indeksi ≥25 olan grupta istatiksiksel olarak anlamli derecede fazla bulundu. Sonuç: Asit reflü sayisi, uzun asit reflü sayisi, pH<4 fraksiyone zaman ve total pH-metre skoru normal kilolu hasta grubunda fazla kilolu ve obez hastalardan anlamli olarak düsük bulundu.
Abstract
Background and Aims: Gastroesophageal reflux disease and obesity are increasingly important health problems. The literature on the relationship between gastroesophageal reflux disease and obesity is conflicting. The most objective method of defining gastroesophageal reflux disease is 24-hour esophageal pH monitoring, which has a high specificity. We planned this retrospective study to investigate if there is a relationship between body mass index (BMI) and pH monitoring data in patients with gastroesophageal reflux disease. Materials and Methods: Data of 207 patients who underwent 24-hour esophageal pH monitoring were analyzed. The demographic characteristics and pH monitoring records were evaluated. The correlation between body mass index and 24-hour esophageal pH monitoring parameters was investigated. The World Health Organization categories of body mass index were used to group the patients. The esophageal 24-hour pH monitoring parameters were compared between body mass index groups. Results: Of the 207 patients, 93 were male (45%), 114 were female (55%) and the mean age was 42 ± 12 (range: 18-74 years). Patients with body mass index <25 were compared with the group of patients with body mass index ≥25. Statistically significant increases in the number of reflux episodes, number of long reflux episodes, fraction time of pH <4, and total De Meester score were observed with body mass index ≥25. Conclusions: The number of reflux episodes and long reflux episodes, fraction time of pH<4 and total De Meester score were statistically lower in patients with normal body mass index than in overweight and obese patients.
