Agustos 2008
Karaciger sirozunda safra kesesi tasi prevalansi
Prevalence of cholelithiasis in cirrhotic patients
- Ana Sayfa
- Sayılar
- Agustos 2008
- Karaciger sirozunda safra kesesi tasi prevalansi...
Özet
Giris ve Amaç: Degisik toplumlar ve ülkeler arasinda safra kesesi tasi varligi asisindan farkliliklar söz konusudur. Ege Bölgesinde sagli kli asemptomatik bireylerde safra kesesi tasi görülme sikligi %7,8 olarak saptanmistir. Karaciger sirozunda safra kesesi tasi görülme sikligi daha fazladir. Bu çalismada Ege Bölgesinde karaciger sirozunda safra kesesi tasi sikligi ve bunun yas, cinsiyet, hastalik etiyolojisi ve evresi ile iliskisinin arastirilmasi planlanmistir. Gereç ve Yöntem: Retrospektif olarak Ocak 1998-2003 tarihleri arasinda klinigimizde yatarak tedavi gören siroz tanili olgularin dosyalari incelenmistir. Çalismaya toplam 294 olgu dahil edilmistir. Karaciger hastaliginin etiyolojisi ve evresi kaydedilmistir. Olgulara üst abdominal ultrasonografik inceleme yapilarak safra kesesi tasi varligi incelenmistir. Bulgular: Hastalarin ortalama yasi 52,6±13,3 yil olup ortalama hastalik süresi 30,7 aydir. 40 olguda ultrasonografik incelemede karaciger sirozuna eslik eden safra kesesi tasi izlenmistir (%13,6). HCV’ye bagli karaciger sirozunda bu oran daha yüksektir. Erkek olgularin 26’sinda kadinlarin 14’ünde safra kesesi tasi saptanmi stir. Safra tasi saptanan olgularin ortalama yasi 54,7±12,8 yil bulunmustur. Sonuç: Sirozlu olgularda safra kesesi tasi görülme sikli- gi yaklasik iki kat artmaktadir. Bu artis kismen HCV varligi ile iliskili görünmektedir. Ileri evre karaciger hastaligi safra kesesi tasi gelisimi için ayrica risk faktörüdür. Sirozlu olgularin safra kesesi tasi açisindan erken tani ve takibi yararli olacaktir.
Abstract
Background and Aims: The prevalence of cholelithiasis differs in different populations. The prevalence was 7.8% in the Aegean region in asymptomatic persons. Liver cirrhosis is considered as a risk factor for the development of cholelithiasis. The aim of this study was to investigate the prevalence of gallstone disease in patients with liver cirrhosis in the Aegean region and to identify risk factors. Materials and Methods: Patients admitted to the gastroenterology inpatient unit with the diagnosis of cirrhosis between January 1998- 2003 were evaluated retrospectively, and 294 patients were included in the study. Etiology of liver cirrhosis and stage of the disease were recorded. The presence of cholelithiasis was evaluated at the time of hospitalization via abdominal ultrasound examination. Results and Conclusions: Mean age of patients was 52.6±13.3 years and duration of the disease was 30.7 months. Ultrasound examination revealed that 40 patients had cholelithiasis accompanying cirrhosis (13.6%). The risk of cholelithiasis was doubled in the presence of liver cirrhosis. Twenty-six males and 14 females had cholelithiasis associated with cirrhosis. Mean age of patients with cholelithiasis was 54.7±12.8 years. Hepatitis C virus-related liver disease and advanced stage of liver cirrhosis were important factors for the higher prevalence of cholelithiasis. Early evaluation and detection of cholelithiasis in cirrhotic patients might be helpful in the follow-up.
