Agustos 2008
Tokat ili eriskinleri’nde kolelitiazis sikligi ve olasi risk faktörleri*
Gallstone disease prevalence in the province of Tokat and possible risk factors*
- Ana Sayfa
- Sayılar
- Agustos 2008
- Tokat ili eriskinleri’nde kolelitiazis sikligi ve olasi risk faktörleri*...
Gaziosmanpasa Üniversitesi Tip Fakültesi, Radyoloji Anabilim Dali2, Iç Hastaliklari Anabilim Dali3, Biyokimya Anabilim Dali4,
Halk Sagligi Anabilim Dali5, Biyoistatistik Anabilim Dali6, Gögüs Hastaliklari Anabilim Dali7, Tokat
Özet
Giris ve Amaç: Safra kesesi taslari dünya genelinde yaygin bir problemdir. Bazi çalismalarda yas, hiperglisemi, dislipidemi, obezite, hizli kilo kaybi gibi faktörlerle kolelitiazis arasinda iliski saptanmi stir. Bu çalismada Tokat ili eriskinleri’nde kolelitiazis ve safra kesesi polip sikligi ve olasi risk faktörlerinin belirlenmesi amaçlanmisti r. Gereç ve Yöntem: Çalisma 18 yas ve üzeri nüfusu yaklasik 530.000 olan Tokat ili’ne bagli 70 merkezde (12 ilçe merkezi ve 58 kirsal bölge) yapildi. Kirsal yerlesim birimleri “Küme Örnekleme Yöntemi” ile seçildi. Çalismaya 530.000 kisi arasindan rasgele örnekleme yöntemiyle seçilen 1.095 kisi (541 erkek ve 554 kadin; kent 555 ve kirsal 540) dahil edildi. Tüm katilimcilarin fizik muayene, ultrasonografi, açlik kan sekeri, total kolesterol, trigliserit, ALT ve AST degerlendirmeleri yapildi. Bulgular: Katilimcilarin yas ortalamasi 41.4±17 (aralik, 18–95) yildi. Kolelitiazis sikligi %7,5, polip sikligi %1,9 bulundu. Kolelitiazis orani kadinlarda erkeklerden yüksekti ve yas, açlik kan sekeri, total kolesterol, trigliserit, beden kitle indeksi, kalça çevresi ve bel/kalça orani ile iliskili bulundu. Sonuç: Çalismamizda Tokat ili eriskinleri’nde kolelitiazis sikligi bati toplumlari’ ndan düsük, Asya verilerinden yüksek ve ülkemizde önceden yapilmis çalismalara benzer bulunmustur.
Abstract
Background and Aims: Gallstone disease is a global health problem worldwide. Positive associations with age, hyperglycemia, dyslipidemia, obesity, and rapid weight loss, etc. have been found in some studies. In the present study, we aimed to determine the prevalence and possible risk factors of gallbladder stone and polyp in urban and rural populations in a northern province of Turkey. Materials and Methods: This study was conducted in 70 areas (12 urban, 58 rural) in the province of Tokat, in the Black Sea region of Turkey, with about 530,000 inhabitants 18 years and older. All urban regions and some rural regions selected by a cluster sampling method were included in the study. The study population of 1,095 subjects (541 M, 554 F; urban 555, rural 540) was selected by a random sampling method among 530,000 individuals. All individuals were evaluated with physical and ultrasonographic examination and some laboratory tests (glucose, total cholesterol, triglyceride, ALT, AST). Results: The mean age of all participants was 41.4±17 years (range: 18–95). We found that the prevalences of cholelithiasis and gallbladder polyp were 7.5% and 1.9%, respectively. Cholelithiasis in women was higher than in men and correlated with age, glucose, total cholesterol, triglycerides, body mass index, waist circumference, hip circumference, and waist-to-hip ratio. Conclusions: We found that the ratio of cholelithiasis in the province of Tokat was lower than in Western populations, higher than in Asian populations, and similar to some previous studies conducted in our country.
