Radyoterapiye sekonder özofagus kanseri: 2 olgu sunumu
Esophageal cancer secondary to radiotherapy: 2 patients
Özet
Radyoterapi komplikasyonlari yeni malignensiler seklinde ortaya çikabilir. Bu çalismada radyoterapi sonrasi özofagus karsinomu gelisen 2 olgu sunulmustur. Yaslari 64 ve 60 olan iki kadin hasta klinigimize yutma güçlügü ve kilo kaybi nedeniyle basvurmustur. Bu hastalara meme kanseri nedeniyle sirasiyla 13 ve 10 yil önce mastektomi ve postoperatif radyoterapi uygulanmistir. Tanisal çalismalarla bu hastalarda skuamöz hücreli özofagus kanseri oldugu ortaya konmustur. Mc Keown ve Threefield prosedürleri cerrahi tedavi olarak uygulanmistir. Radyoterapiye sekonder özofagus malinitesi gelismesi literatürde iyi bilinen konulardan biridir. Erken evre özofagus kanserinin prognozu iyi oldugundan toraks bölgesine radyoterapi uygulanan hastalar özofagus kanseri açisindan yaki n kontrol programina alinmalidir.
Abstract
A complication of radiotherapy is the appearance of new malignancies. In this study, we document two patients with esophageal carcinoma after radiotherapy. Two women, 64 and 60 years old, presented to our department with dysphagia and weight loss. Both had undergone mastectomy and postoperative radiotherapy because of breast carcinoma 13 and 10 years ago, respectively. Diagnostic studies suggested esophageal carcinoma in these patients. Biopsies from the lesions were reported as squamous cell carcinoma. McKeown and Threefield procedures were applied for surgical treatment. Esophageal malignacy secondary to radiotherapy is one of the well-known subjects in literature. Because of the good prognosis in early stage esophageal cancer, patients with a history of radiotherapy to the chest should be monitored with a follow-up program for esophageal carcinoma risk.
