Aralik 2024
Peutz- Jeghers sendromu olan hastalarda çift balon enteroskopinin etkinligi ve güvenliginin degerlendirilmesi: Tek merkez deneyimi
Efficacy and safety of double balloon enteroscopy in patients with Peutz-Jeghers Syndrome: Single center experience
- Ana Sayfa
- Sayılar
- Aralik 2024
- Peutz- Jeghers sendromu olan hastalarda çift balon enteroskopinin etkinligi ve güvenliginin degerlendirilmesi: Tek merkez deneyimi...
2Division of Gastroenterology, Department of Internal Medicine, Ankara University School of Medicine, Ankara, Turkey
Özet
ÖZET •Giris ve Amaç:Peutz-Jeghers sendromlu bireylerde çift balon enteroskopinin klinik sonuçlari hakkindaki bilgilerimiz sinirlidir. Buçalismanin amaci, Peutz-Jeghers sendromlu hastalarda ince bagirsak poliplerinin yönetiminde çift balon enteroskopinin etkinligini ve güvenligini degerlendirmektir.Gereç ve Yöntem:Ocak 2007 ile Mart 2020 tarihleri arasinda merkezimizde çift balon enteroskopi uygulanan 16 Peu-tz-Jeghers sendromlu hastanin verileri toplandi. Çalismaya çapi 1 cm’den büyük polipleri olan hastalar dahil edildi.Bulgular:Peutz-Jegherssendromlu 16 hastaya toplam 79 çift balon enteroskopi prosedürü uygulandi ve 76 oral/anal çift balon enteroskopide 1 cm’den büyük toplam 469 polip bulundu. Ince bagirsak segmentlerinde görülen 80’den fazla polip, intraoperatif çift balon enteroskopi sirasinda endoskopik polipektomikullanilarak çikarildi. Dört hastaya çift balon enteroskopiye ek olarak intraoperatif enteroskopi uygulanmis ve endoskopik polipektomi ile 200’denfazla polip çikarilmistir. 79 çift balon enteroskopi prosedürü sirasinda veya sonrasinda prosedürler ve anestezi ile ilgili toplam 19 komplikasyonmeydana gelmistir. Prosedürle ilgili tüm komplikasyonlar minimal invaziv yöntemlerle tedavi edilmistir. Çift balon enteroskopi sonrasinda iki hasta ameliyat edilmistir (birinde invajinasyon, digerinde adezyon ileusu).Sonuç:Çift balon enteroskopi, Peutz-Jeghers sendromlu hastalarin tani ve uzun dönem takibinde güvenilir ve etkili bir yöntem olarak kabul edilebilir.
Abstract
ABSTRACT • Background and Aims: Our understanding of the clinical outcomes of double balloon enteroscopy in individuals with Peutz-Jeghers syndrome is limited. The purpose of this study is to assess double balloon enteroscopy’s effectiveness and safety in managing small intestinal polyps in Peutz-Jeghers syndrome patients. Materials and Methods: Data from 16 Peutz-Jeghers syndrome patients who underwent double balloon enteroscopy at our center between January 2007 and March 2020 have been collected. The study included patients with polyps larger than 1 cm in diameter. Results: Sixteen patients with Peutz-Jeghers syndrome underwent a total of 79 double balloon enteroscopy procedures, and a total of 469 polyps larger than 1 cm were found in 76 oral/anal double balloon enteroscopies. Over 80 polyps seen in the small intestinal segments were removed using endoscopic polypectomy during intraoperative double balloon enteroscopy. Four patients underwent intraoperative enteroscopy in addition to double balloon enteroscopy and over 200 polyps were removed via endoscopic polypectomy. A total of 19 complications which was related with procedures and anesthesia occurred either during or after the 79 double balloon enteroscopy procedures. All procedure related complications were treated with minimally invasive methods. After double balloon enteroscopy, two patients underwent surgery (one with invagination, the other with adhesion ileus). Conclusion: Double balloon enteroscopy can be considered a reliable and effective method in the diagnosis and long-term follow-up of patients with Peutz-Jeghers syndrome.
