Agustos 2024
Inflamatuvar bagirsak hastaliginda malnütrisyonun yasam kalitesi üzerine etkisi
Effects of malnutrition on quality of life in inflammatory bowel disease
- Ana Sayfa
- Sayılar
- Agustos 2024
- Inflamatuvar bagirsak hastaliginda malnütrisyonun yasam kalitesi üzerine etkisi...
Department of 2Gastroenterology, Lokman Hekim University Akay Hospital, Ankara, Turkey
Department of 3Gastroenterology, Memorial Bahçelievler Hospital, Istanbul, Turkey
Özet
Giris ve Amaç: Inflamatuvar bagirsak hastaliklari seyrinde, hem hastaligin kendisinden hem de kullanilan ilaçlar gibi bazi nedenlerden dolayi malnütrisyon sik görülen bir durumdur. Malnütrisyon ayrica hastalarin morbidite ve mortalite riskinde artisa, tedavi maliyetlerinde artisa ve yasam kalitesinde bozulmaya neden olabilir. Bu nedenle inflamatuvar bagirsak hastaligi olanlar için erken teshis, tedavi ve malnütrisyona iliskin risk faktörlerinin belirlenmesi önemlidir. Çalismamizda inflamatuvar bagirsak hastaligi olanlarda malnütrisyon sikligini, malnütrisyonun genel yasam kalitesine etkilerini, demografik, klinik ve laboratuvar özelliklerini belirlemeyi amaçladik. Gereç ve Yöntem: 2020-2021 yillari arasinda Gastroenteroloji Poliklinigi’ne basvuran inflamatuvar bagirsak hastaligi tanisi alan hastalar MUST skoru ile malnütrisyon riski açisindan tarandi. Hastalarin genel yasam kalitesi EQ-5D indeksi kullanilarak arastirildi. Bulgular: Crohn hastaligi grubundaki hastalarin %11’inde, ülseratif kolit grubundaki hastalarin ise %10’unda malnütrisyon riski yüksekti. Genel yasam kalitesi degerlendirmesinde Crohn hastaligi grubunda EQ-5D indeksi 0.83 ± 0.16, EQ-5D VAS skoru 63.75 ± 19.88; ülseratif kolit grubunda EQ-5D indeksi 0.81 ± 0.19 ve EQ-5D VAS skoru 67.99 ± 22.09 olup, her iki grup genel yasam kalitesi açisindan karsilastirildiginda istatistiksel olarak anlamli bir fark gözlenmedi (sirasiyla p = 0.355, p = 0.202). Crohn hastaligi ve ülseratif kolit tanisi alan hastalarin remisyon ve aktivasyon gruplari malnütrisyon ve genel yasam kalitesi açisindan karsilastirildiginda her iki grup arasinda (aktivasyon ve remisyon) istatistiksel olarak anlamli fark bulunmadi. Sonuç: Hastalarin aktivasyon durumlari, malnütrisyon ve genel yasam kalitesi arasinda anlamli bir iliski bulunamadi. Inflamatuvar bagirsak hastaligi hastalarinda polikliniklerde kilo durumu, beslenme durumu ve genel yasam kalitesinin degerlendirilmesi, profilaktik önlemlerle hastaligin seyri sirasinda olasi malnütrisyon ve genel yasam kalitesinin bozulmasini önleme sansi vermektedir. Malnütrisyonun hastaliklarin prognozu üzerindeki etkisi dikkate alindiginda inflamatuvar bagirsak hastaligi hastalarinin malnütrisyon açisindan degerlendirilmesi oldukça önemlidir.
Abstract
Background and Aims: In the course of inflammatory bowel diseases, malnutrition is a common condition for both the disease itself and some other reasons, such as the drugs used. Malnutrition can also lead to an increase in patients’ risk of morbidity and mortality, an increase in treatment costs and impairment in quality of life. Therefore, early detection, treatment and determination of the risk factors for malnutrition are important for inflammatory bowel diseases patients. In our study, we aimed to determine the frequency of malnutrition, the effects of malnutrition on the overall quality of life, and the demographic, clinical and laboratory features of patients with inflammatory bowel diseases. Materials and Methods: Patients diagnosed with inflammatory bowel diseases who were admitted to Gastroenterology Outpatient Clinic between 2020 and 2021 were screened for the risk of malnutrition by MUST score. The overall quality of life of the patients was investigated using the EQ-5D index. Results: The risk of malnutrition was high in 11% of the patients in the Chron’s disease group and in 10% of the patients in the ulcerative colitis group. In general quality of life evaluation, EQ-5D index was 0.83 ± 0.16 and EQ-5D VAS score was 63.75 ± 19.88 in the Chron’s disease group; in the ulcerative colitis group, the EQ-5D index was 0.81 ± 0.19 and the EQ-5D VAS score was 67.99 ± 22.09, and when both groups were compared in terms of general quality of life, no statistically significant difference was observed (p = 0.355, p = 0.202, respectively). When the remission and activation groups of patients diagnosed with Crohn’s and ulcerative colitis were compared in terms of malnutrition and general quality of life, no statistically significant difference was found between both groups (activation and remission). Conclusion: No significant correlation was found with the activation status of the patients, their malnutrition and general quality of life. Evaluation of weight status, nutritional status and general quality of life in inflammatory bowel diseases patients in polyclinics gives us the chance to prevent possible malnutrition and deterioration of general quality of life during the course of the disease with prophylactic measures. Considering the effect of malnutrition on the prognosis of diseases, evaluation of inflammatory bowel diseases patients in terms of malnutrition is very important.
