Agustos 2022
Dispeptik hastalarda Helicobacter pylori ile duodenumun daginik beyaz noktasal lezyonlari arasindaki iliskinin degerlendirilmesi
Evaluation of the relationship between Helicobacter pylori and duodenal scattered white spots lesions in dyspeptic patients
- Ana Sayfa
- Sayılar
- Agustos 2022
- Dispeptik hastalarda Helicobacter pylori ile duodenumun daginik beyaz noktasal lezyonlari arasindaki iliskinin degerlendirilmesi...
Özet
Giris ve Amaç: Rutin endoskopik degerlendirmede genellikle karsilastigimiz ve intestinal lenfanjiektazi olarak degerlendirdigimiz duodenumun daginik beyaz noktasal lezyonlarinin çogunlukla belirgin bir nedeni veya klinik karsiligi bilinmemektedir. Çalismamizda daginik beyaz noktasal lezyonlarin sikligini, patolojik karsiligini ve Helicobacter pylori ile olan iliskisini degerlendirmeyi amaçladik. Gereç ve Yöntem: Iç Hastaliklari ve Gastroenteroloji Bilim Dalimiz polikliniklerine basvuran ve ayni endoskopist tarafindan dispeptik yakinma sikayeti ile gastroskopileri uygulanan toplam 445 hastanin endoskopi bulgulari retrospektif olarak degerlendirildi. Endoskopik bulgularinda daginik beyaz noktasal lezyonlar saptanan hastalarin antrum ve duodenal biyopsileri alinarak histolojik olarak incelendi. Bulgular: Tüm hastalarin %60’i kadin (n = 245) ve yaslari ortalamasi 47.1 yil idi. Incelenen endoskopik raporlarda 39 (%8.8) hastada daginik beyaz noktasal lezyonlarin oldugu saptandi. Daginik beyaz noktasal lezyonlar saptanan hastalarin biyopsilerinde 10 hastada (%26.3) intestinal lenfanjiektazi, 21 hastada (%55.2) kronik nonspesifik duodenit ve 7 hastada (%18.5) Giardia enfeksiyonu saptandi. Daginik beyaz noktasal lezyonlarin saptandigi hastalarin yarisinda (n = 19) Helicobacter pylori pozitif olarak saptandi (p = 0.695). Helicobacter pylori sikligi patolojik olarak intestinal lenfanjiektazi saptanmis grupta da istatiksel olarak farkli bulunmadi. Sonuç: Dispeptik yakinmalar ile gelen hastalarin gastroskopilerinde daginik beyaz noktasal lezyonlarin sikligi %8.8 olarak bulundu. Bu hastalarin ancak dörtte birinde patoloji ile konfirme intestinal lenfanjiektazi görülmektedir. Daginik beyaz noktasal lezyonlar ve intestinal lenfanjiektazi saptanmasi ile Helicobacter pylori pozitifligi arasinda bir iliski saptanmamistir.
Abstract
Background and Aims: Duodenal scattered white spot lesions, which we usually encounter and evaluate as intestinal lymphangiectasia inroutine endoscopic evaluation, are mostly unknown for a cause or clinical equivalent. In our study, we aimed to evaluate the frequency of duodenal scattered white spot lesions, their pathological findings and their relationship with Helicobacter pylori. Materials and Methods: A totalof 445 patients admitted to Department of Internal Medicine and Gastroenterology and underwent gastroscopy by the same endoscopist whohave dyspeptic complaints. The endoscopy findings of all patients were evaluated retrospectively. Antrum and duodenal biopsies were taken ofpatients with endoscopic findings of duodenal scattered white spot lesions and histologically examined. Results: Two-thirds of the patients werefemale (60%) and the mean age was 47.1 years. The examined endoscopic reports revealed that 39 (8.8%) patients had duodenal scatteredwhite spot lesions. The biopsies of the patients with duodenal scattered white spot lesions revealed intestinal lymphangiectasia in 10 patients(26.3%), chronic nonspecific duodenitis in 21 patients (55.2%), and Giardia infection in 7 patients (18.5%). There were 19 (n = 19) patients withHelicobacter pylori was found to be positive (p = 0.695). The frequency of Helicobacter pylori was also not found to be statistically different inthe pathologically intestinal lymphangiectasia group. Conclusion: The frequency of duodenal scattered white spot lesions in gastroscopies ofpatients with dyspeptic complaints was found to be 8.8%. However, the confirmation of intestinal lymphangiectasia with pathology is observed inonly a quarter of these patients. The detection of duodenal scattered white spot lesions and intestinal lymphangiectasia, there is no correlationbetween Helicobacter pylori positivity.
