Nisan 2021
Akut biliyer pankreatitli hastalarda prognozu öngörmede çeşitli skorlama sistemlerinin karşılaştırmalı değerlendirilmesi
Comparative evaluation of various scoring systems to predict prognosis in patients with acute biliary pancreatitis
- Ana Sayfa
- Sayılar
- Nisan 2021
- Akut biliyer pankreatitli hastalarda prognozu öngörmede çeşitli skorlama sistemlerinin karşılaştırmalı değerlendirilmesi...
Özet
Background and Aims: To identify the severity of pancreatitis in patients diagnosed with acute biliary pancreatitis, and it also seeks to assess the congruence between the revised Atlanta classification and clinical and laboratory findings and prognostic scoring systems. Materials and Methods: A total of sixty-six patients with biliary pancreatitis were evaluated with revised Atlanta classification. Ranson score, Glasgow-Imrie score, Bedside Index of Severity in Acute Pancreatitis, Harmless Acute Pancreatitis Score, Japanese Severity Score, Acute Physiology and Chronic Health Evaluation-II, Sequential Organ Failure Assessment score, albumin-bilirubin score were evaluated and compared, along with clinical and laboratory findings. SPSS Windows version 23.0 and Medcalc 19.2 were used in the analysis. Results: Bedside Index of Severity in Acute Pancreatitis had the highest correlation coefficient in differentiating moderate and severe pancreatitis. Glasgow-Imrie, albumin-bilirubin grade (48 h) and Japanese Severity Score score and Sequential Organ Failure Assessment score were also moderately correlated. Albumin-bilirubin grade (admission) and Harmless Acute Pancreatitis Score were weakly correlated. No correlation was found with the Ranson score and Acute Physiology and Chronic Health Evaluation score. The presence of albumin-bilirubin grade 3 at 48th hour increases the risk of moderate and severe pancreatitis by 17 times. Presence of antibiotic use increases the risk 6.6 times and positive Bedside Index of Severity in Acute Pancreatitis score increases the risk 4.7 times. Conclusion: The use of multiple scoring systems or co-evaluation of laboratory data can increase the sensitivity and specificity of clinical decisions. Combined use of Bedside Index of Severity in Acute Pancreatitis and antibiotherapy requirement is a candidate for predicting moderate and severe pancreatitis. Further studies on albumin-bilirubin grade, especially in acute biliary pancreatitis, are necessary.
Abstract
Background and Aims: To identify the severity of pancreatitis in patients diagnosed with acute biliary pancreatitis, and it also seeks to assess the congruence between the revised Atlanta classification and clinical and laboratory findings and prognostic scoring systems. Materials and Methods: A total of sixty-six patients with biliary pancreatitis were evaluated with revised Atlanta classification. Ranson score, Glasgow-Imrie score, Bedside Index of Severity in Acute Pancreatitis, Harmless Acute Pancreatitis Score, Japanese Severity Score, Acute Physiology and Chronic Health Evaluation-II, Sequential Organ Failure Assessment score, albumin-bilirubin score were evaluated and compared, along with clinical and laboratory findings. SPSS Windows version 23.0 and Medcalc 19.2 were used in the analysis. Results: Bedside Index of Severity in Acute Pancreatitis had the highest correlation coefficient in differentiating moderate and severe pancreatitis. Glasgow-Imrie, albumin-bilirubin grade (48 h) and Japanese Severity Score score andSequential Organ Failure Assessment score were also moderately correlated. Albumin-bilirubin grade (admission) and Harmless Acute Pancreatitis Score were weakly correlated. No correlation was found with the Ranson score and Acute Physiology and Chronic Health Evaluation score. The presence of albumin-bilirubin grade 3 at 48th hour increases the risk of moderate and severe pancreatitis by 17 times. Presence of antibiotic use increases the risk 6.6 times and positive Bedside Index of Severity in Acute Pancreatitis score increases the risk 4.7 times. Conclusion: The use of multiple scoring systems or co-evaluation of laboratory data can increase the sensitivity and specificity of clinical decisions. Combined use of Bedside Index of Severity in Acute Pancreatitis and antibiotherapy requirement is a candidate for predicting moderate and severe pancreatitis. Further studies on albumin-bilirubin grade, especially in acute biliary pancreatitis, are necessary.
