Giris ve Amaç: Direkt etkili anti viral ilaçlarin kullanilmasiyla, hepatit C virüsü enfeksiyonunun tedavisinde basari orani %100’e yaklasmistir. Bununla birlikte, birçok hasta teshis konulmayi beklemektedir. Biz mevcut çalismada cerrahi öncesi hepatit C virüsü taramasi yapilan hastalarda anti-hepatit C virüsü ve hepatit C virüs-RNA pozitifliginin prevalansini belirlemeyi ve hastaligindan habersiz olan hastalarin oranini arastirmayi amaçladik. Gereç ve Yöntem: 2012-2015 yillari arasinda cerrahi kliniklerinde anti-hepatit C virüsü pozitif saptanan hastalar, hepatit C virüs-RNA pozitifligi ve tedavi geçmisi açisindan arastirildi. Hepatit C virüs-RNA pozitifligi açisindan hastane kayitlari tarandi. Tedavi bilgilerine Medula Sisteminden (Sosyal Güvenlik Sisteminden entegre bir veri tabani) ulasildi. Tedavisiz anti-hepatit C virüsü pozitif hastalara telefonla pozitiflikten haberdar olup olmadiklari soruldu. Bulgular: 4 yil boyunca 19627 hasta anti-hepatit C virüsü pozitifligi açisindan tarandi. 158 hastada (%0.8) anti-hepatit C virüsü pozitif bulundu (76 erkek, 82 kadin; yas: 58.2 ± 17.6). Hepatit C virüs-RNA 83 hastada bakilmisti, 75 hastada hepatit C virüs-RNA testi yoktu. Ulasilabilen 58 hastanin sadece 14’ü anti-hepatit C virüsü pozitif oldugunu biliyordu. Diger 44 hasta gastroenteroloji veya enfeksiyon hastaliklari polikliniklerine basvurmalari konusunda uyarildi. Sonuç: Cerrahi girisim uygulanan 19627 hastanin %0.8’inde anti-hepatit C virüsü genel Türkiye nüfusuna benzer oranda pozitif bulunmustur.Hastalarin neredeyse yarisinda hepatit C virüs-RNA test edilmemis ve çogu hasta hepatit C virüsü-RNA’nin test edilmesi ve izlenmesi gerektigi bilgisine sahip degildir. Anti- hepatit C virüsünün cerrahi öncesi taranmasi yeni hastalarin tespiti açisindan yetersiz bulunmustur
Background and Aims: The success rate of hepatitis C virus treatment is ~100% after administration of direct-acting antivirals. However, many patients remain undiagnosed. We determined the prevalence of anti-hepatitis C virus and hepatitis C virus-RNA positivity in patients who were screened for hepatitis C virus before surgical procedures and investigated the rate of awareness of their illness. Materials and Methods: Anti-hepatitis C virus screening data were requested and reviewed from all surgical clinics between 2012 and 2015, and positive patients were evaluated for hepatitis C virus-RNA positivity. Treatment data were collected from the Medula System, an integrated database of the Social Security System. Untreated anti-hepatitis C virus positive patients were contacted by phone and asked whether they were aware of their positivity. Results: A total of 19,627 patients were screened for anti-hepatitis C virus during the study period, of which 158 patients (0.8%) were positive (male: 76; female: 82; age: 58.2 ± 17.6 years). Eighty-three patients were tested for hepatitis C virus-RNA, whereas 75 patients were not. Of the 58 patients who could be contacted, 14 were aware of their anti-hepatitis C virus positivity. The remaining 44 patients were alerted to present to the gastroenterology or infectious diseases outpatient clinic. Conclusion: Among the 19,627 patients screened, 0.8% showed anti-hepatitis C virus positivity, which is similar to the prevalence of anti-hepatitis C virus positivity among the general Turkish population. Almost half of the patients were not tested for hepatitis C virus-RNA, and most of the patients had no information about their anti--hepatitis C virus positivity. These results indicate that presurgical anti-hepatitis C virus screening is insufficient for diagnosing new patients.