Aralik 2017
Karabük ilinde çocuk hastalarda hepatit A, B ve C seroprevalansi
Seroprevalence of HAV, HBV, and HCV in pediatric patients in Karabük province
- Ana Sayfa
- Sayılar
- Aralik 2017
- Karabük ilinde çocuk hastalarda hepatit A, B ve C seroprevalansi ...
Özet
Giris ve Amaç: Bu çalismada Karabük ilindeki çocuklarda Hepatit A, Bve C seroprevalansini saptamayi amaçladik.Gereç ve Yöntem: Kesitseltipteki bu çalisma, Ocak 2015–Aralik 2016 tarihleri arasinda çocuk poliklinigimize farkli sikayetlerle basvurmus 0-18 yas grubu çocuklarda ger-çeklestirildi. Çalismaya alinan çocuklar 0-1 yas, 2-6 yas ve 7-18 yas olmaküzere 3 gruba ayrildi. Çocuklardan alinan kan örneklerinde anti-HAVIgM, anti-HAV IgG, HBsAg, anti-HBs ve anti-HCV degerleri Enzyme-Linked Immunosorbend Assay yöntemi ile test edildi. Bulgular: Çalismayaalinan 2024 hastanin 785’i (%38,8) kiz, 1.239’u (%66,2) erkekti. Hastalarin yaslari 0 ile 18 arasinda olup, yas ortalamasi 10,24±4,71 yil idi. anti-HAV IgM pozitifligi %6,5 ve anti-HAV IgG pozitifligi %28 olarak saptandi. Hastalarin HBsAg, anti-HBs ve anti-HCV seropozitiflikleri; sirasiyla%0,2, %61,1 ve %0,1 olarak saptandi.Sonuç: Ilimiz ve çevresinde dahaönce hepatit A, B ve C seropozitifligini gösteren çalisma yoktur. Ülkemizde hepatit A enfeksiyonunun serolojik prevalansi cografik bölgelerarasinda degiskenlik göstermektedir. Ilimizdeki düsük tespit ettigimizhepatit A seroprevalansi su ve yiyecek hijyeninin iyi kontrol edilmesiyleiliskilendirilebilir. Çalismamizdaki hepatit B ve hepatit C seroprevalansoranlari, ülkemizdeki genel nüfus oranlariyla uyumludur.
Abstract
Background and Aims: In this study, we aimed to investigate hepatitis A, B, and C seroprevalence in children. Materials and Methods:This cross-sectional study was carried out between January 2015 andDecember 2016 in children aged 0–18 years who applied for routinechild examination to our pediatric clinic. The children were divided into3 groups: 0–1 years, 2–6 years, and 7–18 years. Blood samples weretaken from children, and anti-HAV IgM, anti-HAV IgG, HBsAg, anti-HBs,and anti-HCV were determined in each sample using enzyme-linked immunosorbent assay method. Results: A total of 2024 patients wereenrolled in the study, out of which 785 (38.8%) were women and 1239(66.2%) were men. The mean age was 10.24±4.71 years. Anti-HAVIgM and anti-HAV IgG were detected in 6.5% and 28% of the patients,respectively. On the other hand, 0.2%, 61.1%, and 0.1% of patientswere detected seropositive for HBsAg, anti-HBs, and anti-HCV, respectively. Conclusion: There is no previous study showing hepatitis A, B,and C seroprevalence in our province and its surrounding area. The seroprevalence rates of hepatitis A vary geographically in the country. Thelow hepatitis A seroprevalence rate may be associated with the goodlevel of food and water hygiene in the province. In our study, HBV andHCV seroprevalence rates are comparable to the general population.
