Nisan 2016
Bölgemizde Helicobacter pylori sikligi
Helicobacter pylori prevalance in our region
- Ana Sayfa
- Sayılar
- Nisan 2016
- Bölgemizde Helicobacter pylori sikligi...
Özet
Giris ve Amaç: Bu çalismanin amaci, Erzurum bölgesinde endoskopi yapilan hastalarda Helicobacter pylori (H.pylori) sikliginin arastirilarak yillara göre sikligindaki degisiklikleri göstermektir. Gereç ve Yöntem: Subat-Ekim 2015 tarihleri arasinda, endoskopi ünitemizde dispeptik sikayetle basvuran hastalardan, endoskopik antrum ve korpus biyopsisi alinan hastalar, çalismaya alindi ve retrospektif olarak incelendi. Hastalarin H.pylori sikliklari, cinsiyete göre ve yas gruplarina ayrilarak belirlendi. Antrum ve korpus biyopsileri üre içeren besiyerine alinarak hasta basi inkübe edildi. 1.saat ve 24. saatlik inkübasyon sürelerinde, besiyerinin pH indikatörü ile saridan pembeye ve mor renge dogru renk degisikligine bakildi. Pozitif olgularda genellikle ilk 1 saat içinde sonuç alinir. Negatif olanlarda ise duyarliligi artirmak için inkübasyon süresini uzatmak gerekir. Bu testin duyarliligi, bir saat içinde %60-90 iken, 24 saatte ise duyarlilik %90’dan fazladir. Bulgular: Antrum biyopsisi alinan 653 hasta çalismaya alindi. Bu hastalarin 268’i (%41) erkek olup, yas ortalamasi 47.5±16.05 yas (dagilim 15-87) idi. Hastalarin 377’sinde (%57.7) H.pylori pozitif, 276’sinda (%42.2) negatif idi. H.pylori pozitif saptanan hastalarin yaklasik %58.7’sinde hafif (+), %41.2’sinde siddettli (++) pozitiflik olarak rapor edildi. Kadinlarda ve erkeklerde siklik benzer olup sirasiyla %57.6 ve %57.8’ idi. 20 yas alti, 21-40 yas, 41-60 yas, 60 yas üstü yas gruplarinda, H.pylori sikligi sirasiyla, %56.2, %57.7, %59.2 ve %57.3 idi. Sonuç: Erzurum bölgesinde, H.pylori sikligi %57.7 olup yillara göre siklikta azalma izlenmektedir. H. pylori sikligi açisindan, cinsiyet ve yas gruplari arasinda anlamli farklilik bulunmamistir.
Abstract
Background and Aims: The aim of this study is to investigate the prevalence of Helicobacter pylori and the change of prevalence by years in patients underwent endoscopy eastern Anatolia. Materials and Methods: The patients whose endoscopic antrum and corpus biopsies were taken for dyspeptic symptoms in our endoscopy unit in February-October 2015 period were included and retrospectively investigated. The frequency of Helicobacter pylori was determined as separating the patients according to general, sex and the age groups. Antrum and corpus biopsies were stained with urea and incubated per patient. In 1 st hour and 24 th hour incubation periods, it is looked for transitions in the color from yellow to purple and pink by a PH indicator. In positive cases, we can generally get a result in the first hour. In negative ones, to increase the sensitivity, it has to be make the incubation period longer. Although the sensitivity of this test 60-90 % in an hour, it is more than 90% in 24 hours. Results: Biopsy specimens of 653 patients were included into the study. The mean age was 47.5±16.05 years (range 15-87) and 268 of these patients (41%) were male. 377 of the patients (57.7%) were positive and 276 (42.2%) were negative for Helicobacter pylori. It was reported that 58.7% of those patients had mild positive, 41.2% of those had severe positive in infected by Helicobacter pylori. No significant difference was found in the frequency of Helicobacter pylori between women and men, 57.6% and 57.8% respectively. The frequencies of Helicobacter pylori were 56.2%, 57.7%, 59.2% and 57.3%, respectively, in the age groups of under 20 years, 21-40 years, 41-60 years and older 60 years. Conclusion: The frequency of Helicobacter pylori was 57.7% in Erzurum Region and it is observed that it is decreasing in the during the years. No statistically significant difference was found between genders and age groups in term of the frequency of Helicobacter pylori.
