Aralik 2012
Kronik viral hepatitlerde ekstrahepatik bulgular: Günlük klinik pratikte unutulmamasi gereken bir nokta
Extrahepatic manifestations of chronic viral hepatitis: possible associated complications must not be forgotten in daily clinical practice
- Ana Sayfa
- Sayılar
- Aralik 2012
- Kronik viral hepatitlerde ekstrahepatik bulgular: Günlük klinik pratikte unutulmamasi gereken bir nokta...
Özet
Giris ve Amaç:Hepatit etkeni virüsler kronik karaciger hastaliklarina yol açmanin yanisira ekstrahepatik bulgular olarak adlandirilan diger organ ve dokularda da bozukluklara neden olabilirler. Tedavide ekstrahepatik tutulumlari da gözardi etmemek gereklidir. Gereç ve Yöntem: Istanbul Tip Fakültesi Gastroenteroloji Bilim Dali?nda 1997-2010 yillari arasinda takipli toplam 2870 hastada klinik olarak semptomatik ekstrahepatik tutulumu olan 52 hastanin (%2) demografik özellikleri retrospektif olarak degerlendirildi. Bulgular: Elli iki hastadan 27?si (%52) hepatit C, 24?ü (%46) hepatit B ve 1 (%2) hasta da hem hepatit B hem de hepatit C idi. Bunlardan 25?i (%48) erkekti, ortalama yafl 51±13 (18-78) yildi. Otuz iki hasta (%61) sirotik evrede, 20 hasta (%39) ise presirotik evrede idi. Sonuç:Ekstrahepatik tutulumlar genellikle atlanmaktadir. Klinisyenler ekstrahepatik bulgularin tanisinda daha duyarli olmalidirlar.
Abstract
Background and Aims:Hepatitis viruses induce not only chronic liver diseases but also the impairment of other organs and tissues as extrahepatic manifestations. It is necessary to consider possible complications associated with extrahepatic diseases in the treatment.Materials and Methods: We retrospectively evaluated the demographic features of 52 (2%) patients who had clinically symptomatic extrahepatic manifestations from among 2870 chronic viral hepatitis patients in the Gastroenterology Department of the Istanbul Medical Faculty between 1997 and 2010. Results: Twenty-seven of the 52 patients (52%) had hepatitis C, 24 (46%) hepatitis B, and 1 (2%) both hepatitis B and C. Of these, 25 (48%) were males, and the mean age was 51±13 (range, 18 to 78) years. Thirty-two patients (61%) were cirrhotic, while 20 (39%) were in the precirrhotic stage.Conclusions: Extrahepatic involvement is generally overlooked, and clinicians should be more sensitive to the diagnoses of these manifestations.
