Aralik 2009
Servikal özofagustaki heterotopik gastrik mukozanin endoskopik sikligi; bir referans merkez çalismasi
The endoscopic incidence of heterotopic gastric mucosa in the servical esophagus: A referral center study
- Ana Sayfa
- Sayılar
- Aralik 2009
- Servikal özofagustaki heterotopik gastrik mukozanin endoskopik sikligi; bir referans merkez çalismasi...
Özet
Giris ve Amaç: Özofagiyal heterotopik gastrik mukoza çogunlukla özofagusun üst bölgelerinde lokalizedir. Bu nedenle çogu zaman tani konamaz. Biz bu çalismamizda heterotopik gastrik mukoza saptanan hastalarin diger endoskopik bulgularini retrospektif olarak degerlendirdik. Gereç ve Yöntem: Mart 2007- Kasim 2009 tarihleri arasinda 14935 hastaya uygulanan 18522 üst gastrointestinal sistem endoskopisi retrospektif olarak incelendi. Endoskopik özellikler ve heterotopik gastric mukozanin histolojik inceleme sonuçlari kaydedildi. Bulgular: Hastalardan 60 (%0,4) tanesinde heterotopik gastrik mukoza saptandi. Bu hastalarin 12 (%20) tanesinde özofajit mevcut idi. LA grade B özofajit erkeklerde, LA Grade A özofajit ise kadinlarda istatistiksel olarak daha yüksek idi (p: 0.024). Histolojik olarak Barrett özofagusu sadece 1 hastada saptandi. Sonuç: Bu çalismada heterotopik gastrik mukoza sikligi önceki çalismalara kiyasen düsük saptandi. Ayrica heterotopik gastrik mukoza saptanan hastalarin birçogunda üst gastrointestinal sistem endoskopisinde gastroözofagiyal reflü bulgulari mevcuttu.
Abstract
Background and aims: Esophageal heterotopic gastric mucosa mostly presents in the upper part of the esophagus. It is commonly under-diagnosed because of its localization. In this study, we aimed to expose the association between heterotopic gastric mucosa and endoscopic features of the upper gastrointestinal tract. Materials and Methods: A total of 18522 upper endoscopic examinations conducted in 14935 patients between March 2007 and November 2009 were analyzed retrospectively. Endoscopic features and histological examinations of heterotopic gastric mucosa specimens were documented. Results: Heterotopic gastric mucosa was present in 60 (0.4%) of all patients. Twelve (20.0%) patients with heterotopic gastric mucosa had esophagitis. Los Angeles Grade B esophagitis was significantly high in males, while Los Angeles Grade A esophagitis was found to be significantly high in females (p: 0.024). Histologically proven Barrett?s esophagus was detected in only 1 patient. Conclusions: In this study, incidence of heterotopic gastric mucosa was found to be low compared with previous reports. Further, endoscopic examination of the upper gastrointestinal tract showed that many patients with heterotopic gastric mucosa have endoscopic signs of gastroesophageal reflux.
