Bu çalışmada yerinde sitopatolojik inceleme yapilamayan ortamda pankreas gövde kesimde yerlesik fokal pankreatik kitlelerden örnek alinmasinda 19-gauge endoskopik ultrason - ince igne aspirasyon biyopsisi ile 19 gauge endoskopik ultrason tru-cut biyopsinin örneklemedeki hücresel yeterliligini ve güvenilirligini karsilastirmayi amaçladık. Gereç ve Yöntem: Izmir Atatürk Egitim ve araştırma Hastanesi Gastroenteroloji kliniginde endosonografi kullanilarak doku örneklemesi yapılan 48 hasta çalışmaya dahil edildi. Bir gruba (n=26) 19 gauge endoskopik ultrason ince igne aspirasyon ile, diğer gruba (n=22) 19 gauge tru-cut biopsi ile pankreas kitle örneklemesi yapildi. Bulgular: Islem tekrar sayisina bakilmaksizin, yeterli örnekleme yapilma orani 19- gauge ince igne aspirasyon biyopside %92.3 ve 19 gau- ge tru-cut biyopside %90.9, ince igne aspirasyon biyopsisi grubunda 1. seansta hücresel yeterlilik orani %69.2 % , tru-cut biyopsi grubunda 1. seansta hücresel yeterlilik orani %72.7 idi (p>0 ,05). Ince igne aspirasyon biyopsiside hücre blogu elde edilme orani %23 iken, tru-cut biyopsi’de %45 idi (P<0,005). Isleme bagli komplikasyonlar açısından fark saptanmadi. Sonuç: 19-gauge endoskopik ultrason - ince igne aspirasyon biyopsisi ile 19 gauge endoskopik ultrason tru-cut biyopsinin hücresel yeterlilik açısından benzer derecede etkin ve güvenilir ancak hücre blogu elde etme oraninin endoskopik ultrason tru-cut biyopsi grubunda belirgin daha yüksek olduğunu saptadik.
In this study, we aimed to compare the reliability and efficiency of 19 gauge fine needle aspiration and 19 gauge TruCut needle biopsy in the sampling of pancreatic body mass with endosonography, in those conditions when diagnosis cannot be made by on-site pathological evaluation. Materials and Methods: Forty-eight patients seen at Izmir Ataturk Training and Research Hospital, Department of Gastroenterology, in whom pancreatic body mass sampling was performed with endosonography were enrolled in this study. 19 gauge endosonography with fine needle aspiration was performed in one group (n=26) and 19 gauge Tru-Cut needle biopsy sampling in the other (n=22). Results: An adequate sampling rate was achieved regardless of the number of sessions, with 92.3% with 19 gauge fine needle aspiration and 90.9% with 19 gauge Tru-Cut needle biopsy. Adequacy of cellularity ratio in the first session was 69.2% with fine needle aspiration and 72.7% with Tru-Cut needle biopsy (p>0.05). While the ratio of obtaining cell block from fine needle aspiration was 23%, this ratio was 45% with Tru-Cut needle biopsy (p<0.005). There was no difference in terms of procedure-related complications. Conclusions: 19 gauge endosonography - fine needle aspiration and 19 gauge endosonography -Tru-Cut needle biopsy were similarly effective and reliable in terms of cellular adequacy, but the ratio of obtaining cell block was significantly higher in the Tru-Cut needle biopsy group than the fine needle aspiration group.